Spravato® is the first FDA approved prescription nasal spray for treatment-resistant depression, providing relief in as little as 24 hours.
Spravato (esketamine) is a prescription nasal spray that is used to treat adults with treatment-resistant depression (TRD), or major depressive disorder with suicidal ideation.
Unlike oral antidepressants, Spravato is a novel mechanism that acts on different receptors (NMDA vs. serotonin receptors) to treat depression and bring fast relief.

For adults struggling with
treatment-resistant depression (TRD) and major depressive disorder (MDD) with suicidal thoughts or actions.
About 70% of patients show a clinically meaningful response, with treatments easily integrated into your life.
Spravato is covered by several major insurance payers, including Medicare and Medicaid, making it an accessible option for many if you've tried antidepressants and therapy.
Induction: Twice weekly for the first 4 weeks
Maintenance: Once weekly for the following 4 weeks
After this 8-week treatment course, you will meet with your provider to discuss the best treatment cadence going forward..
Following administration, you will be observed for 2 hours by your provider
Patient cannot drive from their appointment on treatment days due to side effects, find your ride!


Dr. Pritham Raj is a board-certified expert in internal medicine and psychiatry, specializing in the connection between mental and physical health. He earned his medical degree from the University of Maryland and completed a combined residency at Duke University, where he contributed to early TMS research.
Dr. Raj’s research focuses on obesity, depression, and cognitive health. Passionate about wellness, he trained as a Chief Wellness Officer at Stanford University and has provided expert insights on the mental and physical impacts of the COVID-19 pandemic. Outside of work, he enjoys time with his children and leads DARK to Light, a nonprofit supporting children of separating families.
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